Efficacia della melatonina nella prevenzione, trattamento e gestione di delirio e demenza senile

Recenti studi clinici hanno dimostrato che la melatonina puņ essere utile nella prevenzione, trattamento di delirio e la gestione di demenza senile.

Melatonin based therapies for delirium and dementia.

Discov Med. 2016 May;21(117):363-371

Authors: Alagiakrishnan K

Melatonin levels have been shown to decline with aging. Melatonin and its analogs in addition to their effect on sleep promotion, has been shown to have multiple pleiotropic effects. It can also help with neuroprotection through different mechanisms. Evidence in animal and human studies suggests that low levels of melatonin have been linked to delirium, mild cognitive impairment, dementia, and with certain behavioral problems. Recent clinical trials have showed that both melatonin and its analogs may be useful in the prevention, treatment of delirium, and the management of dementia. These medications seem to have the advantage of less side effects and better safety profile when compared to antipsychotics and sedatives like benzodiazepines. These medications are available over the counter in North America, Europe, and Asia, and some of these medications are approved by FDA. This manuscript will discuss the promising role of these melatonergic medications alone or in combination with other medications for the management of Geriatric Psychiatric diseases like delirium and dementia.

PMID: 27355332 [PubMed - as supplied by publisher]

Share |

Melatonina.it l'unico portale interamente dedicato alla melatonina in italia
Versione multilingue del sito Key Melatonin

Sito conforme al prov. n. 229 - 08/05/2014 Codice Privacy in quanto utilizza esclusivamente cookies tecnici

Clavis Chitosano Vegetale
Integratore alimentare a base di CHITOSANO VEGETALE ( KiOnutrime-Cs ).
Chitosano Vegetale

Clavis Harmoniae
Clavis Harmoniae

Key Alghe
Linea di integratori alimentari a base di alghe
Key Alghe