Effetti della melatonina nel trattamento delle malattie cardiovascolari: i progressi nel corso dell'ultimo anno

Numerosi studi hanno suggerito che la melatonina svolge un ruolo importante in varie malattie cardiovascolari. Gli studi presi in esame, in questo articolo scientifico, hanno dimostrato che la melatonina ha effetti significativi nei danni da ischemia-riperfusione, ipertensione polmonare, ipertensione, malattie delle valvole cardiache, malattie vascolari, e il metabolismo dei lipidi. La melatonina può essere una nuova opzione terapeutica per il trattamento delle malattie cardiovascolari.

Effects of melatonin on cardiovascular diseases: progress in the past year.
Curr Opin Lipidol. 2016 Apr 12;
Authors: Sun H, Gusdon AM, Qu S

Abstract
PURPOSE OF REVIEW: Melatonin is a neuroendocrine hormone synthesized primarily by the pineal gland. Numerous studies have suggested that melatonin plays an important role in various cardiovascular diseases. In this article, recent progress regarding melatonin's effects on cardiovascular diseases is reviewed.
RECENT FINDINGS: In the past year, studies have focused on the mechanism of protection of melatonin on cardiovascular diseases, including myocardial ischemia-reperfusion injury, myocardial hypoxia-reoxygenation injury, pulmonary hypertension, hypertension, atherosclerosis, valvular heart diseases, and other cardiovascular diseases.
SUMMARY: Studies have demonstrated that melatonin has significant effects on ischemia-reperfusion injury, myocardial chronic intermittent hypoxia injury, pulmonary hypertension, hypertension, valvular heart diseases, vascular diseases, and lipid metabolism. As an inexpensive and well tolerated drug, melatonin may be a new therapeutic option for cardiovascular disease.

PMID: 27075419 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/27075419?dopt=Abstract